Main Timeline Video Share
May the Holiday Warm Hearts: Idram and IDBank Support the Children of Heroes Beneficiaries of the "By Your Side" program at IDBank AraratBank Named Large CSR Company of the Year Idram Joins the Fight Against Food Insecurity Ucom’s Renovated Sales and Service Center in Yerevan Mall Reopens 1% idcoin instead of New Year’s suffering: practical tips Idram Junior Donated Books to Schools Big Christmas Market with Idram, IDBank and idplus Ucom Supports Wildlife Monitoring in Ararat Region IDBank, Idram, and idplus at the Big Christmas Market Converse Bank Deputy CEO and CFO, Grant Akopian, Elected to BACEE Board Ucom and SunChild NGO Install a Solar Plant in Alaverdi Kindergarten
Beating the heat, earning idcoins: Idram & IDBankUnibank - the Main Sponsor of the Velosolutions UCI Pump Track World Championship Qualifier in Armenia What to do If you’ve already become a victim of fraudIdram and IDBank participated in Sevan Startup SummitArmenian National Festival Takes Place under AraratBank's SponsorshipArmDrone Community will launch a One-Month Free Educational Program with Ucom’s SupportAmeriabank Receives Euromoney Award for Excellence 2025 as the Best Bank in ArmeniaAraratBank's “The Will to Get Back on Your Feet Again” Film Series to Be Featured at Armenian National FestivalOnline Payments via ApplePay Now Available for vPOS Clients of AmeriabankUcom Subscribers Increasingly Use Internet While RoamingHorizon Camp: With AraratBank's Support - Towards Leadership and Financial LiteracyIdram at Tech Week 2025Idram and Alipay+ Facilitate Cross-Border QR Payments in Armenia, Connecting Local Merchants with Global Digital Wallet Users"Business Process Optimization with AI" – a Course for the Senior Management of AraratBank A Protected Ecosystem thanks to Advanced Technology: Ucom and FPWC Join Forces DIALOG Organization - Partner of the “Born in Artsakh” ProgramMoody's upgrades Converse Bank's ratingsAraratBank participated in the WEPs regional experience-sharing workshopIDBank issues the 3rd, 4th and 5th tranches of bonds of 2025AraratBank: Special Rate for SWIFT Transfers up to EUR 20,000
Life

Scientists explain emergence of especially dangerous pathogens of tuberculosis

In a new study, published in the journal Bioorganic Chemistry, scientists have explained why Mycobacterium tuberculosis survives in inappropriate environmental conditions inside the human body.

The results of this study may help to better understand the role of enzymes in bacteria in the development of resistance against the human immune system and drugs.

The authors of the study examined the crystal structure and function of rubredoxin B (RubB), a metalloprotein (a protein containing metal atoms) that ensures the proper functioning of cytochrome P450, another protein important for bacterial survival. Scientists have a hypothesis, according to which, tubercle bacilli have learned to switch rubredoxin into a mode that ensures the effective use of iron in conditions of iron deficiency, which is observed during the formation of granulomas (nodules) in the lungs.

As a result, it turned out that rubredoxin B is associated with heme monooxygenases, which are important for the metabolism of oxysterols (they play a signaling role in the maintenance of immunity) and the host's anti-tuberculosis drugs. In other words, M. tuberculosis has the ability to neutralize xenobiotics.

Previous research has shown that one of the cytochromes supported by RubB may act against SQ109, a promising potential drug for multidrug-resistant tuberculosis.

According to the WHO, every year around the world 10 million people fall ill with tuberculosis, and 1.5 million people die from it, which makes it the main infectious killer in the world. Particularly dangerous strains of the tubercle bacillus, which have appeared in recent decades, have multiple drug resistance, mainly antibiotics, which greatly complicates the treatment of the infection.